Diversity and circulation of Jingmen tick virus in ticks and mammals

dc.contributor.author Guo, Jing Jing
dc.contributor.author Lin, Xian Dan
dc.contributor.author Chen, Yan Mei
dc.contributor.author Hao, Zong Yu
dc.contributor.author Wang, Zhao Xiao
dc.contributor.author Yu, Zhu Mei
dc.contributor.author Lu, Miao
dc.contributor.author Li, Kun
dc.contributor.author Qin, Xin Cheng
dc.contributor.author Wang, Wen
dc.contributor.author Holmes, Edward C.
dc.contributor.author Hou, Wei
dc.contributor.author Zhang, Yong Zhen
dc.date.accessioned 2022-01-29T03:05:23Z
dc.date.available 2022-01-29T03:05:23Z
dc.date.issued 7/1/2020
dc.description.abstract Abstract Since its initial identification in ticks in 2010, Jingmen tick virus (JMTV) has been described in cattle, rodents, and primates. To better understand the diversity, evolution, and transmission of JMTV, we sampled 215 ticks, 104 cattle bloods, 216 bats, and 119 rodents in Wenzhou city, Zhejiang Province, China as well as 240 bats from Guizhou and Henan Provinces. JMTV was identified in 107 ticks (from two species), 54 bats (eleven species), 8 rodents (three species), and 10 cattle, with prevalence levels of 49.8, 11.8, 6.7, and 9.6 per cent, respectively, suggesting that bats may be a natural reservoir of JMTV. Phylogenetic analyses revealed that all the newly identified JMTVs were closely related to each other and to previously described viruses. Additionally, all tick and mammalian JMTV sampled in Wenzhou shared a consistent genomic structure, suggesting that the virus can cocirculate between ticks and mammals without observable variation in genome organization. All JMTVs sampled globally could be divided into two phylogenetic groups, Mantel tests suggested that geographic isolation, rather than host species, may be the main driver of JMTV diversity. However, the exact geographical origin of JMTV was difficult to determine, suggesting that this virus has a complex evolutionary history.
dc.identifier.other 10.1093/ve/veaa051
dc.identifier.uri https://data.tickbase.net/handle/20.500.13086/3985
dc.title Diversity and circulation of Jingmen tick virus in ticks and mammals