The special role of CXCL13 in Lyme neuroborreliosis: a case report

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Date
1/17/2022
Authors
Erhart, Deborah K.
Bracknies, Vera
Lutz-Schuhbauer, Susanne
Wigand, Sonja
Tumani, Hayrettin
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Abstract
AbstractThe diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.
Description
The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.
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 https://data.tickbase.net/handle/20.500.13086/3937
DOI
10.1186/s42466-022-00167-y
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