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The text discusses the arrival of warmer weather and its correlation with the onset of tick-borne diseases, specifically mentioning Lyme disease. It also hints at the emergence of new tick-borne illnesses during this season.

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Tularemia, a zoonotic disease primarily found in the Northern Hemisphere, can be transmitted through inhalation or tick and flying insect vectors. The bacteria Francisella tularensis, which causes tularemia, is highly infectious and poses a potential bioterrorism threat.

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Loudoun County, Virginia, has been declared an epidemic region for Lyme disease, a bacterial illness transmitted by ticks. The increase in Lyme disease cases is linked to the suburbanization and creation of habitats favorable to ticks and mice hosts, coinciding with the real estate bubble during the Alan Greenspan era.

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Forty or more cell lines from various tick species are available, providing a platform for studying interactions between tick cells and pathogens. The utility of these tick cell lines is expected to increase with the advent of genetic transformation and RNA interference techniques.

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Research into tick toxins has revealed potential pharmacological targets, suggesting a possible advancement in the scientific understanding of ticks.

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Rabbits were immunized with haemolymph components from Rhipicephalus appendiculatus ticks and subsequently challenged with all developmental instars. The rabbits developed resistance to all tick stages, with the resistance being more pronounced in adult ticks, manifesting as reduced numbers of engorged ticks, lower engorgement weights, and decreased fecundities. This resistance was maintained in subsequent infestations.

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The text introduces a new model, Tree-HAR, designed for estimating and predicting tick-by-tick realized correlations, particularly in the context of S&P 500 Futures and 30-year Treasury Bond Futures. The model demonstrates accuracy in both single and multi-step out-of-sample forecasts, outperforming other standard approaches.

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The text is a response to John Tulloch's research comment on the risk of tickborne diseases to UK pets. It emphasizes the need for further research into the prevalence of tick-borne diseases in domestic pets within the UK, mentioning Babesia canis and Borrelia burgdoferi as examples.

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The text proposes a tree-structured heterogeneous autoregressive (tree-HAR) process model to estimate and predict tick-by-tick realized correlations, accounting for different time and relevant predictors' dependent regime shifts. The model is tested on S&P 500 and 30-year treasury bond futures, showing accurate single- and multi-step out-of-sample forecasts, outperforming other standard approaches.

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Tick bite prevention and tick removal

BMJ (Clinical research ed.)

2013 15 citations

This text is a summary of information about ticks, their physical characteristics, life cycles, and the diseases they transmit. It explains that ticks are small blood-feeding parasites with a global distribution, and that they can transmit various disease pathogens including rickettsiae, spirochaetes, and viruses. The text also details the physical differences between hard and soft ticks, their life cycles, and the sizes of different tick stages.

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Hypersensitivity reactions to tick and other arthropod bites are common, particularly with ixodid (hard bodied) ticks. These ticks transmit infections to humans worldwide and cause most vector-borne diseases in the US. The immune response to repeated tick exposure can interfere with the blood meal and potentially prevent pathogen transmission. Human studies on tick bite hypersensitivity have included local and generalized reactions, and progress in anti-tick vaccine development for humans has recently accelerated.

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Tick trouble: overview of tick-borne diseases

Cleveland Clinic journal of medicine

2000 7 citations

The text discusses the importance of early identification and treatment of tick-borne diseases, including Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, and babesiosis. It emphasizes the need for primary care physicians to be knowledgeable about the epidemiology and symptoms of these diseases due to their widespread occurrence in the United States.

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Ticks are significant vectors of human diseases, second only to mosquitoes. Various in vitro and in vivo assays have been developed to identify repellents for ticks. These repellents can be used topically or in impregnated clothing to prevent tick bites and potential pathogen transmission. Currently, synthetic molecules like DEET, IR3535, picaridin, KBR 3023, para-menthanediol, and permethrin are commercialized. There is ongoing research to identify new repellent molecules, including plant-derived ones as alternatives to synthetics.

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Ixodid Tick Dissection and Tick Ex Vivo Organ Cultures for Tick-Borne Virus Research

Current protocols in microbiology

2020

Advanced Summarizations Available

This text provides step-by-step procedures for setting up tick organ cultures, which can be used for virus infection and functional genomic studies. These procedures can help identify susceptible cell types of tissue to infection and pinpoint tick-specific genes involved in the virus lifecycle.

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Tick anaphylaxis triggered by pulling out the tick

Takayama Noriya, Takagaki Yusaku

Acute medicine & surgery

2020 1 citations

Advanced Summarizations Available

A case of tick anaphylaxis, a rare occurrence in Asian countries, is reported. The reaction was triggered by pulling out the tick from a 66-year-old man's toe, leading to anaphylactic shock. This is believed to be the first such case in an Asian country.

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This review discusses the role of tick pheromones in regulating various behaviors such as assembly, attraction, aggregation, attachment, and mating. The pheromones are primarily composed of purines, substituted phenols, or cholesteryl esters, with other compounds like organic acids, hematin, or ecdysteroids also present. The review also highlights the effectiveness of novel devices that combine these specific pheromone compounds with an acaricide for tick control when applied to vegetation or animal bodies.

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Tick-bite fever, a rickettsial disease found in southern Africa, is transmitted by ixodid ticks. The infection spreads through generations of ticks and can be passed to humans through tick bites, causing symptoms like fever, muscle pain, and delirium. Diagnosis can be confirmed in the lab, and the illness can be treated with chloramphenicol and tetracycline antibiotics. Ticks are avoided to prevent infection, and experimental vaccines have been developed.

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A partially engorged female Rhipicephalus hmaphysaloides paulopunctatus Neumann was observed feeding on a fully engorged female BoSphilus microplus (Canestrini) in the Netherlands East Indies. This is considered an instance of accidental parasitism rather than cannibalism, as it involves ticks of different species and genera. Previous instances of 'cannibalism' have been reported among same-species ticks.

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Tick Talk: Tick-borne Diseases of South Dakota

South Dakota medicine : the journal of the South Dakota State Medical Association

South Dakota

2017 1 citations

This article provides a review of ticks and tick-borne diseases relevant to South Dakota and surrounding regions, highlighting diseases such as tularemia, Rocky Mountain spotted fever, and Lyme disease. It emphasizes the importance of prompt treatment and using preventive measures to reduce the risk of acquiring these diseases, many of which are nationally reportable infectious diseases.

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This research focuses on the protein trafficking in tick salivary glands, particularly examining the role of SNAPs and SNAREs in exocytosis. The study aims to understand how tick cells regulate the movement of proteins from granular acini to saliva.

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